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Can Wisdom Teeth Stem Cells Be Used to Treat Corneal Scarring?

Posted by: Dr. Sirakian     Categories: Uncategorized

A scarred or scratched cornea is a condition that necessitates immediate treatment, and it could potentially lead to permanent vision loss. As of now, the options to treat this scarring include donor corneas replacing the damaged one, or donor tissues to try and regenerate the impaired tissue. However, teeth may provide another option!

Recent findings at the University of Pittsburgh School of Medicine indicate that the “stem cells from the dental pulp of wisdom teeth can be coaxed” to become cornea cells and thus repair scarring. Becoming blind from cornea damage is said to affect millions of people around the world. If the wisdom teeth pulp option helps to heal this, it could be a major advancement in treatment.

The biggest issue with current treatment options is the lack of donor corneas; when donor tissue can be implanted, there is also the risk of the tissue being rejected by the recipient’s body. So how do wisdom teeth stem cells avoid these risks? According to the Pittsburg School of Dental Medicine, wisdom teeth pulp could be turned into “keratocytes, which have the same embryonic origin,” making the cells a better fit to repair the cornea.

As of now, the research has been tested on laboratory mice to see the effects firsthand. The results of injecting keratocytes into mice corneas showed perfect integration with no signs of rejection. Because this was only the first test, researchers will continue to test on other animal models better judge the pulp’s effectiveness.

Also, according to Dr. Syed-Picard of Pittsburgh’s Department of Ophthalmology, there is proven research showing that dental pulp has serious potential for use in “regenerative purposes and making neural, bone, and other cells.” If these theories of dental pulp are proven 100% right, then the future of corneal scarring could be changed for the better, helping millions worldwide avoid the damages. Who would have thought teeth would be an answer to vision loss?

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Oct
23

What Your Bone Type Could Mean For Dental Implant Treatment

“It depends.” That’s probably an answer you will often hear if you’re considering getting dental implants. This is because there are so many things to consider when placing a dental implant. One of the many considerations that your dentist needs to take into account before placing a dental implant is what type of bone you […]

Oct
15

The Battleground At the Root of An Infected Tooth

When a tooth is so badly infected that the bacteria make their way through the entire tooth and reach the gums beneath, the result is a painful infection at the base of the tooth (known as a periapical lesion). In addition to the general inflammatory pain at the site of infection, any pressure applied on […]

Oct
8

Please, Please, Please Don’t File Down Your Teeth

We’ve seen a disturbing trend on TikTok where people, mostly teens, have been filing down their front teeth in order to make them ‘even’ or ‘straight’. We can’t believe we have to say this, but please don’t do it. We can’t stress enough just how bad this is, but let’s discuss the gruesome details of […]

Oct
1

The Time Right After Your Tooth-Whitening Treatment is Critical

Teeth bleaching has been shown to be an effective and lasting treatment for stained teeth time and again. With the right treatment protocols, some patients even report white teeth lasting for a year or more. But regardless of which tooth bleaching treatment you get, here are some things to know if you want to maximize […]

Sep
24

What Are Periodontal Pockets and Can You Keep Your Phone In One?

We’ll start off by making it clear that, no, you can’t keep anything in your periodontal pockets. In fact, the smaller they are the better. You may not notice it, but your gums are not completely attached to your teeth at the gum line. At first there’s actually a small gap between the tooth and […]

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